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Welcome to Niner Noise\u2019s live game thread for the 49ers\u2019 Week 1 matchup against the Lions. Discuss the game with writers and fans in the comments section!<\/i><\/strong><\/p>\n

The San Francisco 49ers kick off the 2021 NFL regular season with a trip to the Eastern Time Zone  to take on the Detroit Lions at Ford Field in Detroit, MI. The game will begin at 1 p.m. ET on Sunday, September 12, 2021.<\/p>\n

49ers backup quarterback and No. 3 overall draft pick Trey Lance<\/a> is expected to see his first regular season NFL action in the game. He will not be joined by second-rounder and offensive lineman Aaron Banks or third-round running back Trey Sermon, both of whom are healthy scratches for the game.<\/p>\n

Probably a bit of a surprise there, but head coach Kyle Shanahan regularly goes with whoever he thinks will play best regardless of draft status.<\/p>\n

Fifth-round corner Deommodore Lenoir<\/a> is expected to start the game in place of CB Emmanuel Moseley, who is out with a knee injury<\/a>. Interior defensive lineman Javon Kinlaw will likely have to wait until Week 2 before he plays his first game in 2021.<\/p>\n

49ers vs. Lions: How to watch<\/strong><\/h2>\n

Today\u2019s showdown between the Niners and Lions will be broadcast on FOX Sports. Broadcast coverage will feature play-by-play and color commentator Mark Sanchez \u2014 and with Laura Okmin on the sideline. The game will be shown on channel 711 on DIRECTV\u2019s NFL Sunday ticket.<\/p>\n

49ers fans in local markets can stream the game on 49ers.com or via the 49ers.com app. An additional streaming option is fuboTV, which includes a free seven-day trial for first-time users<\/a>.<\/p>\n

Enjoy the 49ers\u2019 first game of the 2021 NFL regular season<\/a> with us in the comments section:<\/p>\n

Join in the discussion with Niner Noise writers and fellow fans in our new comments section, \u201cThe Conversation,\u201d at the bottom of the article!<\/strong><\/p>\n

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