The San Francisco 49ers (6-9) return to action in their penultimate contest of the 2024 NFL season.
The 49ers’ Monday Night Football matchup against the Detroit Lions (13-2) doesn’t bring the type of implications for both that many would have forecasted when this 2024 campaign began.
In a rematch of last season’s NFC Championship game, the 49ers can only aspire to play late-season spoiler for Detroit. San Francisco has already been eliminated from playoff contention, but Detroit has its sights set on locking up the No. 1 seed in the NFC.
If the 49ers are to indeed play spoiler, they will have to do so in spite of a dicey injury report.
As kickoff nears, here’s a look at the latest odds for the matchup, including the point spread, money line numbers and the over-under total. Plus, a prediction for how the matchup unfolds.
49ers vs. Lions game odds:
All NFL Odds via BetMGM:
- Point spread: Detroit -3.5
- Money line: Detroit -200 / San Francisco +165
- Over-under: 50.5
49ers vs. Lions injury updates:
- 49ers OL Aaron Banks – OUT (knee)
- 49ers OL Spencer Burford – OUT (calf)
- 49ers DL Robert Beal Jr. – OUT (ankle)
- 49ers LB Dre Greenlaw – OUT (calf)
- 49ers OL Colton McKivitz – Questionable (knee)
- 49ers S Ji’Ayir Brown – Questionable (ankle)
- 49ers CB Charvarius Ward – Questionable (personal matter)
- Lions RB David Montgomery – OUT (knee)
- Lions WR Kalif Raymond – OUT (foot)
- Lions LB Jalen Reeves-Maybin – Questionable (neck)
49ers vs. Lions prediction, pick:
Prediction: Detroit 30, San Francisco 17
The 49ers’ offensive line and running backs are incredibly banged up. That makes life difficult for San Francisco quarterback Brock Purdy. While the Lions are dealing with their own rash of injuries, Jared Goff and Detroit deliver and exact revenge in a game where they have much more at stake.
49ers vs. Lions channel, start time, streaming:
The 49ers vs. Lions game starts at 5:15 p.m. PT and can be seen on ESPN or ABC.
Get more betting analysis and predictions at Sportsbook Wire.
About the Author: Insidethe49
