Now that we have the 49ers’ 53-man roster and the NFL calendar turns to the regular season, we can start parsing through the players San Francisco will take into their trek for another Super Bowl run.
Below is our best guess at what the 49ers’ depth chart will look like when the face the Detroit Lions in Week 1. The offense is set for 22 personnel (two tight ends, two running backs). The defensive line and linebacker starters are for the base 4-3 defense, and the cornerback group is listed out for their nickel package.