The San Francisco 49ers (1-1) will visit the Denver Broncos (1-1) on Sunday at 8:20 PM ET.

Defensively, the 49ers have been a top-five unit, ranking best by giving up only 210 yards per game. They rank 15th on offense (352 yards per game). The Broncos rank seventh in the NFL with 391.5 total yards per game, but they’ve been led by their defense, which ranks third-best by allowing only 243.5 total yards per contest.

Read below where we dig deep into all of the details you need before this contest starts, including how to watch on TV.

49ers vs Broncos: Live Streaming Info, TV Channel & Game Time

  • Game Day: Sunday, September 25, 2022
  • Game Time: 8:20 PM ET
  • Location: Denver, Colorado
  • Stadium: Empower Field at Mile High
  • TV Channel: NBC
  • Live Stream: fuboTV (Watch for free)

49ers vs Broncos Betting Lines

College football odds courtesy of Tipico Sportsbook. Odds updated Wednesday at 12:48 AM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread Favorite: 49ers (-1.5)
  • Moneyline: 49ers (-123), Broncos (+102)
  • Total: 45 Points

OFFER: Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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