San Francisco 49ers v Cleveland Browns
Photo by Michael Zagaris/San Francisco 49ers/Getty Images

The 49ers will look to start fast, as they always do. But this time around, they’ll hope to hold the lead.

We’ve seen the 49ers bounce back and forth between 7.5 and 6.5 point favorites, and the line finally settles at 7 on DraftKings Sportsbook with the total on the game set at 44.5.

There isn’t an offense in the NFL that’s been more effective on its opening drives than San Francisco. Kyle Shanahan has helped scheme the 49ers offense to score a league-high 38 points.

Defensively, Dre Greenlaw back in the fold should be a big help. His intensity and overall effectiveness was missed against Cleveland. It feels like a night where the defense is poised to give Kirk Cousins and the Minnesota Vikings hell.

It’s worth noting that Kevin O’Connell coached with Sean McVay for multiple years, so he has plenty of familiarity with what the Niners want to do. But he doesn’t have the players, and Minnesota looked like a team out of answers a week ago.

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